CLARENCE, N.Y.--(BUSINESS WIRE)--22nd Century Group, Inc. (NYSE MKT: XXII), a leader in very low nicotine tobacco technology and tobacco harm reduction, held its annual meeting of shareholders on Saturday, April 25, 2015, at the historic Buffalo Club in downtown Buffalo. Henry Sicignano III, President and CEO, addressed the following topics: Modified Risk/FDA: The Company intends to submit an application for its very low nicotine cigarette (Brand A) to the FDA this summer. Gaining Modified Risk